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What is Phentermine?
Phentermine is a stimulant similar to an amphetamine. It’s an appetite suppressant that affects the central nervous system.
Adipex is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Adipex may also be used for purposes not listed in this medication guide.
Phentermine indications
Adipex is indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).
How should I use Phentermine ?
Use Phentermine orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Phentermine orally disintegrating tablets by mouth with or without food.
- Take Phentermine orally disintegrating tablets in the morning unless your doctor directs you otherwise. Taking Adipex orally disintegrating tablets in the evening may cause trouble sleeping.
- Make sure that your hands are dry before removing Phentermine orally disintegrating tablets from the bottle. Place the tablet on the top of your tongue where it will dissolve. The tablet dissolves quickly and can be swallowed with saliva. Phentermine orally disintegrating tablets may be taken with or without water. Take the tablet immediately after removing it from the bottle. Do not store the removed tablet for future use.
- If you miss a dose of Phentermine orally disintegrating tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Phentermine orally disintegrating tablets.
Uses of Phentermine in details
Phentermine is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.
It is not known how this medication helps people to lose weight. It may work by decreasing your appetite, increasing the amount of energy used by your body, or by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.
How to use Phentermine
Take this medication by mouth as directed by your doctor, usually once a day, 1 hour before breakfast or 1 to 2 hours after breakfast. If needed, your doctor may adjust your dose to take a small dose up to 3 times a day. Carefully follow your doctor’s instructions. Taking this medication late in the day may cause trouble sleeping (insomnia).
If you are using sustained-release capsules, the dose is usually taken once a day before breakfast or at least 10 to 14 hours before bedtime. Swallow the medication whole. Do not crush or chew sustained-release capsules. Doing so can release all of the drug at once, increasing the risk of side effects.
If you are using the tablets made to dissolve in the mouth, the dose is usually taken once a day in the morning, with or without food. First, dry your hands before handling the tablet. Place your dose on top of the tongue until it dissolves, then swallow it with or without water.
The dosage is based on your medical condition and response to therapy. Your doctor will adjust the dose to find the best dose for you. Use this medication regularly and exactly as prescribed in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.
This medication is usually taken for only a few weeks at a time. It should not be taken with other appetite suppressants. The possibility of serious side effects increases with longer use of this medication and use of this drug along with certain other diet drugs.
This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as depression, severe tiredness) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.
Rarely, abnormal drug-seeking behavior (addiction) is possible with this medication. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.
This medication may stop working well after you have been taking it for a few weeks. Talk with your doctor if this medication stops working well. Do not increase the dose unless directed by your doctor. Your doctor may direct you to stop taking this medication.
Phentermine Results
According to the National Institutes of Health, the average weight loss for patients on medications like Phentermine is approximately 5 to 10 pounds.
What does Phentermine do to the body?
It stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. Phentermine is used together with diet and exercise to treat obesity, especially in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
What are the bad side effects of Phentermine ?
The more common side effects of Phentermine can include:
bad taste in your mouth.
constipation.
diarrhea.
dry mouth.
headache.
vomiting.
How long can you take Phentermine ?
Phentermine is a prescription medication given to assist people with weight loss. It works by decreasing the appetite and is usually prescribed for three to six weeks (though can be used for up to 12 weeks) to people who are exercising and eating a low-calorie diet.
What should I eat while taking Phentermine ?
Good sources of protein are skinless chicken and turkey, tofu, fish, low-fat dairy, lean beef, eggs, and nuts. Fiber: While fiber is not a magic weight-loss weapon, healthy high-fiber foods make you feel full, so you can resist eating more food than you need.
Can you be on Phentermine long term?
The researchers found that at 24 months, longer-term users of Phentermine had more weight loss, with patients using continuously for >12 months losing 7.4 percent more than those who used for no more than three months.
Phentermine dosage
Exogenous Obesity Dosage should be individualized to obtain an adequate response with the lowest effective dose.
The usual adult dose is one tablet as prescribed by the physician, administered in the morning, with or without food. Phentermine is not recommended for use in pediatric patients less than or equal to 16 years of age.
Late evening medication should be avoided because of the possibility of resulting insomnia.
How supplied
Dosage Forms And StrengthsOrally disintegrating tablets (ODT) containing 15 mg, 30 mg, or 37.5 mg Adipex hydrochloride (equivalent to 12 mg, 24 mg, or 30 mg Adipex base, respectively). The tablets are not scored. The 15 mg ODT is yellow with blue spots round tablet embossed with AX4 on one side. The 30 mg ODT is a yellow round tablet embossed with AX7 on one side. The 37.5 mg ODT is a white with blue spots round tablet embossed with AX8 on one side.
Storage And Handling
Available as orally disintegrating tablets (ODT) containing 15 mg, 30 mg, or 37.5 mg of Adipex hydrochloride (equivalent to 12 mg, 24 mg, or 30 mg Adipex base, respectively). The tablets are not scored. The 15 mg ODT is yellow with blue spots round tablet embossed with AX4 on one side. The 30 mg ODT is a yellow round tablet embossed with AX7 on one side. The 37.5 mg ODT is a white with blue spots round tablet embossed with AX8 on one side.
Adipex is available as described in Table 2.
Table 2: Adipex
Adipex® may decrease the hypotensive effect of adrenergic neuron blocking drugs.
Drug Abuse And Dependence
Adipex is a Schedule IV controlled substance.
AbuseAdipex is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Adipex should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.
Dependence
Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.
Phentermine side effects
In addition to its needed effects, some unwanted effects may be caused by Phentermine (the active ingredient contained in Adipex). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Phentermine :
Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Phentermine if you are pregnant.
Do not use Phentermine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Taking Phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension.
Do not take Phentermine with any other diet medications without your doctor’s advice.
Phentermine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of Phentermine .
Phentermine is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Phentermine may be habit-forming and should be used only by the person it was prescribed for. Never share Phentermine with another person, especially someone with a history of drug abuse or addiction. Keep track of the amount of medicine used from each new bottle. Phentermine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Do not stop using Phentermine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Phentermine .
Phentermine is a prescription medicine similar to amphetamine. Phentermine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.
Phentermine is an appetite suppressant that affects the central nervous system.
Phentermine is used together with diet and exercise to treat obesity, especially in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Do not use Phentermine if you are pregnant or breast-feeding a baby.
You should not use Phentermine if you have glaucoma, overactive thyroid, severe heart problems, uncontrolled high blood pressure, advanced coronary artery disease, extreme agitation, or a history of drug abuse.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. A dangerous drug interaction could occur.
You should not use Phentermine if you are allergic to phentermine, or if you have:
- a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, stroke);
- severe or uncontrolled high blood pressure;
- overactive thyroid;
- glaucoma;
- extreme agitation or nervousness;
- a history of drug abuse; or
- if you take other diet pills.
Do not use Phentermine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use phentermine if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
You should not breast-feed while using Phentermine .
To make sure Phentermine is safe for you, tell your doctor if you have:
- heart disease or coronary artery disease;
- a heart valve disorder;
- high blood pressure;
- diabetes (your diabetes medication dose may need to be adjusted); or
- kidney disease.
Phentermine is not approved for use by anyone younger than 16 years old.
Take Phentermine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Phentermine is usually taken before breakfast, or 1 to 2 hours after breakfast. Follow your doctor’s dosing instructions very carefully.
Never use phentermine in larger amounts, or for longer than prescribed. Taking more of this medication will not make it more effective and can cause serious, life-threatening side effects.
Phentermine is for short-term use only. The effects of appetite suppression may wear off after a few weeks.
Phentermine may be habit-forming. Misuse can cause addiction, overdose, or death. Selling or giving away phentermine is against the law.
Call your doctor at once if you think this medicine is not working as well, or if you have not lost at least 4 pounds within 4 weeks.
Do not stop using this medicine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Usual Adult Dose for Obesity:
8 mg orally 3 times a day 30 minutes before meals, OR
15 to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast.
Use: Short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity in patients with an initial body mass index (BMI) of 30 kg/m2 or greater, or BMI of 27 kg/m2 or greater in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).
Usual Pediatric Dose for Obesity:
Age 17 Years and Older:
8 mg orally 3 times a day 30 minutes before meals, OR
15 to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast.
Use: Short-term (a few weeks) adjuncts in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity in patients with an initial body mass index (BMI) of 30 kg/m2 or greater, or BMI of 27 kg/m2 or greater in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).
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